Botox Guide
Portland, OR · November 8, 2026
By Cosmetiq Medicine · 9 min read
How many units of Botox you need depends on the area, and for the four approved areas the FDA label gives an exact starting dose: 20 units for frown lines, 24 for crow’s feet, 40 for the forehead with frown lines, and 26 to 36 for neck bands. This guide walks through each area, the off-label ones people ask about most, and what those units cost in Portland and Vancouver, WA.
Botox units chart
Labeled doses from the BOTOX Cosmetic prescribing information. Prices at Cosmetiq Medicine’s regular $12 a unit.
Frown lines (11s)
20 units
4 units at 5 points
FDA-labeled $240
Crow’s feet
24 units
12 per side, 3 points each
FDA-labeled $288
Forehead with frown lines
40 units
20 forehead + 20 frown
FDA-labeled $480
Frown lines with crow’s feet
44 units
20 + 24
FDA-labeled $528
Forehead, frown lines and crow’s feet
64 units
20 + 20 + 24
FDA-labeled $768
Neck bands (platysma)
26 to 36 units
Depends on number of bands
FDA-labeled $312 to $432
Masseter (jaw)
24 to 60 units
Range reported in research reviews
Off-label Priced by units used
Lip flip
About 4 units
Dose used in a 2026 study
Off-label Priced by units used
Your injector sets your units at your assessment. Glow members pay $11 a unit and Elite members $10.
How many units of Botox do most people need?
For a first treatment of the most common areas, the labeled doses add up to 20 units for frown lines alone, 40 units for the forehead with frown lines, and 64 units for the full upper face. Those figures come from the BOTOX Cosmetic prescribing information and are the reference point injectors adjust from.
Units are a measure of biological activity, not volume. Botox Cosmetic comes in 50-unit and 100-unit vials and is diluted so that a standard 0.1 mL injection carries 4 units. That is why labeled doses come in multiples of 4: five points of 4 units for the frown lines, three points of 4 units on each side for crow’s feet.
Your own number can differ from the label because muscle strength, the depth of your lines and the look you want all vary. A good consultation explains where the units go and why, and gives you the total before treatment starts.
How many units of Botox for the forehead?
The FDA label doses forehead lines at 20 units across five points in the frontalis muscle, and it labels them to be treated together with the frown lines at another 20 units. That makes 40 units the labeled forehead treatment.
The pairing is deliberate. The forehead muscle raises the brows, and the label studies treated it alongside the muscles that pull the brows down and together. In those studies the most frequently reported adverse reactions with the 40-unit dose were headache (9%), brow ptosis (2%) and eyelid ptosis (2%), according to the prescribing information.

How many units of Botox for 11 lines and frown lines?
The 11 lines between the brows are labeled at 20 units: 4 units into each of five points, two in each corrugator muscle and one in the procerus.
At Cosmetiq Medicine that is $240 at the regular price, $220 for Glow members and $200 for Elite members. If you are comparing toxins, note that the label states Botox units cannot be compared to or converted into units of other botulinum toxin products. Our guide to Botox vs Dysport explains why a Dysport quote uses different numbers.
How many units of Botox for crow’s feet?
Crow’s feet are labeled at 24 units, given as 4 units into three points on each side, or 12 units per eye. Treated together with frown lines the labeled total is 44 units, and with the forehead added it is 64 units.
In the label, eyelid edema (1%) was the most frequently reported adverse reaction for crow’s feet treatment.
How many units of Botox for neck bands?
Neck bands are labeled at 26, 31 or 36 units depending on how many bands you have. Every dose includes 16 units along the jawline (2 units at four points per side) plus 1 unit at five points along each vertical band. The FDA approved this use on October 18, 2024.
One band on each side totals 26 units, one band on one side and two on the other totals 31, and two bands on each side totals 36. At $12 a unit that is $312 to $432.
How many units of Botox for the masseter and jaw slimming?
Masseter treatment is off-label, so there is no FDA dose. A 2025 review in the journal Toxins reports that recommendations most commonly use 24 to 60 units of onabotulinumtoxinA in total, and a 2023 review of studies in Asian patients found 10 to 45 units per side.
The Toxins review by Ferrillo and colleagues also notes that a single higher-dose point is faster but may give uneven reduction, which is why multi-point technique is common. The review of masseter prominence studies adds that a larger or thicker side is usually treated with more units. Because this is off-label, your injector explains the evidence and risks before suggesting a dose.
How many units of Botox for a lip flip?
A lip flip is also off-label. A 2026 prospective study in Aesthetic Plastic Surgery treated 17 women with 4 units of onabotulinumtoxinA in the upper lip, and Cleveland Clinic describes about 2 to 4 units in the upper lip and 2 in the lower.
The 2026 study concluded that the lip flip projects the upper lip by relaxing muscle, not by adding volume, which is why it is often compared with filler. A 2025 systematic review in the Archives of Dermatological Research covers the technique and outcomes reported so far, and Cleveland Clinic summarizes the typical approach. If you want added volume rather than a subtle roll, lip filler in Portland is the treatment to compare.
How much do Botox units cost in Portland?
At Cosmetiq Medicine, Botox is $12 a unit, $11 for Glow members and $10 for Elite members, at both the Portland and Vancouver, WA clinics. Labeled frown lines cost $240, the forehead with frown lines $480, and the full upper face $768 at the regular price.
Frown lines, 20 units
Regular $240
Glow $220
Elite $200
Crow’s feet, 24 units
Regular $288
Glow $264
Elite $240
Forehead and frown lines, 40 units
Regular $480
Glow $440
Elite $400
Full upper face, 64 units
Regular $768
Glow $704
Elite $640
Neck bands, 26 to 36 units
Regular $312 to $432
Glow $286 to $396
Elite $260 to $360
Pricing by the unit means you pay for what your muscles need, not a flat area fee. See Botox in Portland for booking and the full treatment page, the Portland med spa price list for every service, and our current Botox specials for limited-time offers. If you are in Clark County, the Botox in Vancouver, WA page has the same unit pricing. Our guide to judging cheap Botox offers explains why a low per-unit price can still mean a higher total.
How long does each Botox treatment last?
According to the American Academy of Dermatology, most people see results within 3 to 7 days, and the improvement lasts about 3 to 4 months, sometimes longer. The units you receive, the area and your muscles all influence how long your result holds.
Our article on how long Botox lasts covers what affects duration in more detail. If you treat regularly, an Elite or Glow membership lowers every future unit.
What to ask at your Botox consultation
- How many units are you recommending for each area, and how does that compare with the labeled dose?
- Is any area you are suggesting off-label, and what is the evidence for it?
- What is my total before we start, and will I pay for a touch-up?
- Which product are you using, and why that one for my muscles?
- What side effects should I watch for, and how do I reach you afterward?
Botox units FAQ
How many units of Botox do you need for the forehead?
The FDA label doses forehead lines at 20 units across five injection points, and it treats them together with the frown lines, which add another 20 units. That puts a labeled forehead treatment at 40 units in total, or $480 at Cosmetiq Medicine’s regular $12 a unit.
How many units of Botox for 11 lines?
The 11 lines between the brows, called glabellar or frown lines, are labeled at 20 units: 4 units into each of five points. At $12 a unit that is $240, or $200 on an Elite membership.
How many units of Botox for crow’s feet?
The FDA-labeled dose for crow’s feet is 24 units, 12 per side, given as 4 units into three points beside each eye. That comes to $288 at the regular price.
How many units of Botox for a lip flip or masseter?
Both are off-label uses with no FDA-labeled dose. A 2026 prospective study used 4 units in the upper lip, and reviews of masseter research describe total doses of 24 to 60 units. Your injector sets the units after assessing the muscle.
How long do Botox units last?
The American Academy of Dermatology says most people see results within 3 to 7 days and that improvements last about 3 to 4 months, and sometimes longer.
The bottom line
The FDA label gives clear starting doses: 20 units for frown lines, 24 for crow’s feet, 40 for the forehead with frown lines, 64 for all three and 26 to 36 for neck bands. Off-label areas like the masseter and lip flip rely on published studies and your injector’s assessment. At our Portland med spa and Vancouver, WA clinic, you get the unit count and total before treatment begins.
Find out exactly how many units you need
Book Botox at our Portland SE Stark St clinic or our Vancouver, WA clinic. Your injector confirms the units and your total first.
Book in PortlandBook in VancouverSources
- BOTOX Cosmetic (onabotulinumtoxinA) prescribing information, 2024 (accessdata.fda.gov)
- AbbVie: BOTOX Cosmetic receives FDA approval for platysma bands (Oct 18, 2024) (news.abbvie.com)
- Ferrillo et al., The Role of Botulinum Toxin for Masseter Muscle Hypertrophy, Toxins, 2025 (pmc.ncbi.nlm.nih.gov)
- Botulinum Toxin Type A for the Treatment of Masseter Muscle Prominence in Asian Populations, Aesthet Surg J Open Forum, 2023 (pmc.ncbi.nlm.nih.gov)
- Lip Flip Revisited: Clinical Outcomes and Neuromodulatory Basis of Upper Lip Eversion, Aesthetic Plastic Surgery, 2026 (link.springer.com)
- Pitchford et al., The lip flip: a systematic review of botulinum toxin lip augmentation, Arch Dermatol Res, 2025 (pubmed.ncbi.nlm.nih.gov)
- Cleveland Clinic: Lip flip (clevelandclinic.org)
- American Academy of Dermatology: Botulinum toxin therapy overview (aad.org)
This article is for general education and is not medical advice. BOTOX Cosmetic is FDA-approved for frown lines, crow’s feet, forehead lines and platysma bands; other uses are off-label. Treatment suitability and dosing are determined at an in-person consultation. Individual results vary.

