As reported by researchers, the main differences between Botox® and Dysport ® is the onset of action. Dysport ® tends to show effect sooner, working within 2-5 days. Botox® takes slightly longer, starting in 4-7 days. However, it is recommended that no additional units be added to the same treatment area within 2 weeks to avoid overtreatment.

Botox® monopolized the U.S market for many years until 2009, when Dysport® was approved by the FDA.  Dysport® however, was used in Europe many years before it was made available in the United States.